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| Section | Weight | Objectives |
|---|---|---|
| Laboratory Operations | 5-10% | - Laboratory safety and regulatory compliance - Laboratory mathematics and instrumentation - Pre-analytical, analytical, and post-analytical processes - Quality control and quality assurance |
| Microbiology | 15-20% | - Specimen collection and culture techniques - Mycology, parasitology, and virology - Identification of pathogenic microorganisms - Bacteriology and antimicrobial susceptibility |
| Immunology and Serology | 5-10% | - Immune system principles and components - Autoimmune and immunodeficiency disorders - Immunologic testing methodologies - Infectious disease serology |
| Hematology | 20-25% | - Red blood cell physiology and disorders - Routine and automated hematology procedures - Hemostasis and coagulation testing - White blood cell morphology and diseases |
| Blood Banking (Immunohematology) | 15-20% | - Blood components and storage - Blood group systems and antigens - Antibody detection and identification - Compatibility testing - Transfusion reactions and adverse events |
| Urinalysis and Other Body Fluids | 5-10% | - Semen and amniotic fluid testing - Physical, chemical, and microscopic analysis - Urine formation and composition - Cerebrospinal, serous, and synovial fluids |
| Clinical Chemistry | 20-25% | - Electrolytes, acid-base balance, and blood gases - Endocrinology and therapeutic drug monitoring - Toxicology and liver/kidney function tests - Carbohydrates, lipids, proteins, and enzymes |
1. Vitamin K dependent factors are those that require Vitamin K for their synthesis in the liver. Vitamin K is an important factor to gamma-glutamyl carboxylase which adds a carboxyl group to glutamic acid residues on factors II, VII, IX and X, as well as Protein S, Protein C. In adding the gamma-carboxyl group to glutamate residues on the immature clotting factors Vitamin K is itself oxidized. Deficiency of Vitamin K due to malabsorption, liver disease, etc. may contribute to bleeding disorders because clotting factor maturation depends on Vitamin K.
Which of these coagulation factors are referred to as "vitamin-K dependent?"
A) II, VII, IX, X
B) XI, XII, Fletcher, Fitzgerald
C) II, V, IX, XII
D) I, V, VIII, XIII
2. This is the total magnification of the high dry objective lens.
A) 40X
B) 1000X
C) 400X
D) 100X
3. Provide the equivalent measurement for 1 centimeter.
Question options:
A) 5 millimeters
B) 1 inch
C) 1 kilometer
D) 10 millimeters
4. The federal government has categorized critical biological agents into three groups: A, B, and C. Those agents in category A are highest-priority because they can be easily disseminated or transmitted person-to-person.
The federal government has categorized critical biological agents into three groups: A, B, and C. Those agents in category A are highest-priority because they:
A) Can be easily disseminated or transmitted person-to-person.
B) Cause moderate morbidity and low mortality.
C) Could be engineered for mass dissemination at some future date.
5. In combined fiscal years 2005 through 2009, transfusion-related acute lung injury (TRALI) caused the higest number of reported fatalities (48%), followed by hemolytic transfusion reactions (26%) due to non-ABO (16%) and ABO (10%) incompatibilities. Complications of microbial infection, transfusion-associated circulatory overload (TACO), and anaphylactic reactions each accounted for a smaller number of reported fatalities.
A) Anaphylactic reactions
B) Transfusion-associated graft versus host disea
C) Febrile non-hemolytic reactions
D) Transfusion-related acute lung injury (TRALI)
Solutions:
| Question # 1 Answer: A | Question # 2 Answer: C | Question # 3 Answer: D | Question # 4 Answer: A | Question # 5 Answer: D |
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